Conformational Analysis of Isolated Domains of Helicobacter pylori CagA
نویسندگان
چکیده
منابع مشابه
Conformational Analysis of Isolated Domains of Helicobacter pylori CagA
The CagA protein of Helicobacter pylori is associated with increased virulence and gastric cancer risk. CagA is translocated into the host cell by a H. pylori type IV secretion system via mechanisms that are poorly understood. Translocated CagA interacts with numerous host factors, altering a variety of host signalling pathways. The recently determined crystal structure of C-terminally-truncate...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0079367